Fri Apr 11 2025

26 articles - From Friday Apr 04 2025 to Friday Apr 11 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

High-dose docosahexaenoic acid for bronchopulmonary dysplasia severity in very preterm infants: a collaborative individual participant data meta-analysis.

Neonatal enteral supplementation with high-dose DHA was not significantly associated with severe BPD in very preterm infants.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

A mixed-methods study of the drivers of stunting reduction among children under five in Nigeria, 2008-2018.

Participants identified a range of policies and programs across multiple sectors as having likely contributed to the decline in stunting prevalence. A multisectoral approach to stunting reduction in Nigeria appears to have been key, with progress having been driven by both the health sector and, especially, non-health sector action.

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A mixed-methods study of the drivers of stunting reduction among children under-5 in Ghana, 2003-2017.

Of 134 nutrition-related policies and programs identified in our review, 23 national initiatives were assessed as having contributed importantly to reducing stunting in Ghana, reflecting the effectiveness of multisectoral action. Stunting reduction can be accelerated even further in Ghana through increased coverage of high-quality nutrition-specific interventions and greater health and nonhealth sector investments.

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A mixed-methods study of the drivers of stunting reduction among children under-5 in Sierra Leone, 2005-2017.

Rapid reduction in under-5 stunting in Sierra Leone coincided with strong economic growth and declining urban poverty, along with high-profile health and development policies supported by external partners that targeted and/or benefited poorer and rural populations especially. Had the Ebola and COVID-19 epidemics not occurred, positive pre-2014 trajectories in child growth and other maternal and child health and nutrition outcomes in Sierra Leone may well have continued, yielding gains even larger than those observed over the study period.

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Drivers of anemia reduction among women of reproductive age in Pakistan: a mixed-methods country case study.

OBDA explained 89% of the observed change in mean hemoglobin, with household enrollment in the Benazir Income Support Program (36%), household wealth (17%), and improvement in women's nutrition [body mass index (in kg/m2): 15%, serum retinol: 12%] emerging as the most critical drivers of anemia decline among nonpregnant women in Pakistan. To protect these gains and continue improvements, anemia prevention efforts should continue to focus on improving healthcare access, women's economic empowerment, and poverty alleviation.

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Drivers of anemia reduction among women of reproductive age in Uganda: a country case study.

To protect the hard-fought gains and continue improvements, WRA anemia prevention efforts in Uganda should remain focused on improving health care access especially within antenatal care and malaria control programs. Additionally, multisectoral collaborations and investments to empower women and poverty alleviation strategies need to be enhanced.

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Investigating the impact of body composition on the estimation of resting metabolic rate: new equations for adults aged ≥65 years developed using cross-sectional data.

New prediction equations predict RMR at the population level with minimal bias; however, the difference in performance with anthropometry-based equations is minimal. This may be explained by the contribution of FFM to weight, whereby equations that include weight are already accounting for FFM.

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Methods Matter for Dietary Supplement Exposure Assessment: Comparing Prevalence, Product Types, and Amounts of Nutrients from Dietary Supplements in the Interactive Diet and Activity Tracking in AARP Cohort Study.

Within IDATA, the comparability of ASA24 and DHQII in estimating the prevalence of use of and nutrient intakes from DS fluctuates by nutrient and product type. DS approaches beyond a questionnaire may be warranted for estimating absolute nutrient amounts, and the choice of the DS assessment method depends on the nutrient/dietary component of interest.

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Phosphate-based additives in processed foods: is excess exposure a cause for concern? A cross-sectional examination of the United States packaged food supply.

This study illustrates widespread exposure to P-additives in al packaged food and beverage categories in the United States, with sales-weighted data showing a high volume of purchases even in categories containing a lower percentage of products with P-additives. Research exploring the safety of excessive P-additive exposure in CKD and healthy populations requires the Food and Drug Administration to make labeling of the total phosphorus content on nutrition facts labels mandatory.

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Social sector drivers and stunting reduction in Pakistan: A subnational analysis.

Although national progress in stunting reduction remains slow, regions of KP, Northern, and Southern Punjab have demonstrated significant reductions in child stunting prevalence between 2011 and 2018. Our analysis supports continued investments in social sector programs targeting females' health and status and strengthening the reach and quality of existing maternal and child health and nutrition programs.

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What works for anemia reduction among women of reproductive age? Synthesized findings from the exemplars in anemia project.

A context-specific, multisectoral approach is needed to decrease WRA anemia, incorporating direct nutritional interventions and indirect strategies within the health and nonhealth sectors. Lessons from the successes and challenges from exemplar countries could help accelerate global anemia reduction.

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What works for reducing stunting in low-income and middle-income countries? Cumulative learnings from the Global Stunting Exemplars Project.

In malarial endemic areas, malaria control programs were associated with improved childhood growth, and patterns of growth indicated continued benefits of childhood disease prevention and management strategies. A systematic, evidence-informed approach to improve maternal and child health and nutrition is feasible and, with targeting, can accelerate reduction in linear growth faltering in childhood.

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Inflamm Bowel Dis

Assessment and Impact of Age on the Safety and Efficacy of Etrasimod in Patients With Ulcerative Colitis: A Post Hoc Analysis of Data From the ELEVATE UC Clinical Program.

The safety profile of etrasimod 2 mg QD in the ELEVATE UC population was consistent across age groups, with no change in the incidence of AEs. Patients receiving etrasimod vs placebo showed significant clinical benefit, regardless of age. NCT03945188; NCT03996369.

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Health Outcomes, Discrimination, and Stigma Among Sexual and Gender Minority People With Inflammatory Bowel Disease.

SGM individuals with IBD are more likely to experience discrimination, including in healthcare, and illness-related stigma. These may significantly impact the quality of life and should be considered in the care of SGM people with IBD.

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Incidence of Osteoporosis and Osteopenia in Newly Diagnosed Inflammatory Bowel Disease: A Population-Based Cohort Study.

This population-based study demonstrated high rates of osteoporosis among postmenopausal women and males aged ≥ 50 years at IBD diagnosis, highlighting the need for systematic evaluation in these patients.

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J Crohns Colitis

Association of Bile Acid Diarrhea with Symptoms and Disease Activity in Crohn's Disease: Post-Hoc Clinical Trial Analysis of Serum 7a-hydroxy-4cholestern-3-one, C4, in Patients with Active Crohn's Disease.

ClinicalTrials. gov NCT02065570.

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Effectiveness and safety of rectal tacrolimus in patients with ulcerative colitis. TACRO-TOPIC study of GETECCU.

Adverse events were detected in 21 patients (14.2%), with twelve graded as mild and nine moderate (42.6%). Topical tacrolimus is an effective therapy and could be considered in distal UC patients before initiating other advance therapies when endoscopic activity remains.

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Pancreatology

Anticoagulation for splanchnic vein thrombosis in acute pancreatitis increases bleeding risk without improving outcomes.

Approximately half of patients who develop SVT after AP receive AC despite no reduction in adverse events or mortality. Additionally, half of patients receiving AC experience bleeding complications. The limited evidence presented in this study suggests that the risks of AC for SVT in AP may outweigh its benefits and highlights the need for future studies in larger prospective cohorts.

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Reintroduction of palliative intent FOLFIRINOX chemotherapy in a real world pancreatic cancer cohort.

Reintroduction of FOLFIRINOX after at least 3 months therapy-free interval is used in daily practice and seems a reasonable treatment option based on a favorable OS and PFS in a small subset of patients.

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Splanchnic vein thrombosis in patients with pancreatitis: Outcome and impact of anticoagulation.

Non-recanalization was the only risk for portal hypertension. Our study suggests an absence of benefit of anticoagulation.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Predicting resting energy expenditure.

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Inflamm Bowel Dis

Gut Feelings Matter: The Unresolved Questions of Irritable Bowel Syndrome-Like Symptoms in Inflammatory Bowel Disease in Remission.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Efficacy of Mirikizumab in Patients with Prior Ustekinumab Exposure: A Case Series.

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Letter: Predictors of Complicated Disease Course in Children and Adults With Ulcerative Colitis-Authors' Reply.

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Liver Transpl

A survey of national practice patterns of hepatocellular carcinoma surveillance for patients with fontan-associated liver disease: A call to action.

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Pancreatology

Portal venography and portal venous pressure assessment following total pancreatectomy and islet autotransplantation using a recanalised umbilical vein.

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Letters&Replies

Letters to the editors and authors’ replies